ALEXANDRIA, Va., June 18 -- United States Patent no. 12,324,927, issued on June 10, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Methods and systems for photodynamic therapy calculations" was invented by Timothy C. Zhu (Glen Mills, Pa.) and Arjun G. Yodh (Merion, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and systems are described for implementing a photodynamic therapy. An example method may comprise determining, during photodynamic therapy and using a plurality of optical probes spatially distributed within a patient, data indicative of one or more of a photodynamic therapy dosage, a fluence rate of a photodynamic therapy treatment light, or a reactive oxy...