US Patent Issued to The Trustees of the University of Pennsylvania on July 8 for "Compositions and methods for generating a persisting population of T cells useful for the treatment of cancer" (Pennsylvania, New Jersey Inventors)

ALEXANDRIA, Va., July 9 -- United States Patent no. 12,350,334, issued on July 8, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Compositions and methods for generating a persisting population of T cells useful for the treatment of cancer" was invented by Matthew J. Frigault (Philadelphia), Yangbing Zhao (Lumberton, N.J.), John Scholler (Narberth, Pa.) and Carl H. June (Merion Station, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides compositions and methods for generating a genetically modified T cells comprising a chimeric antigen receptor (CAR) having an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a...