US Patent Issued to The Trustees of the University of Pennsylvania on Jan. 27 for "Neuroprotective gene therapy targeting the AKT pathway" (Pennsylvania Inventors)

ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,533,423, issued on Jan. 27, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Neuroprotective gene therapy targeting the AKT pathway" was invented by Jean Bennett (Bryn Mawr, Pa.), Devin McDougald (Philadelphia) and Junwei Sun (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for the treatment of retinal degeneration are provided. In one aspect, provided herein is adeno-associated virus (AAV) vector comprising an AAV capsid having encapsidated therein a vector genome comprising AAV inverted terminal repeat (ITR) sequences, a human protein kinase B (AKT) coding sequence, and expression con...