US Patent Issued to The Trustees of the University of Pennsylvania on Feb. 4 for "Compositions and methods for targeting GammaDelta T cells with chimeric antigen receptors" (Pennsylvania Inventors)

ALEXANDRIA, Va., Feb. 5 -- United States Patent no. 12,215,154, issued on Feb. 4, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Compositions and methods for targeting GammaDelta T cells with chimeric antigen receptors" was invented by Aimee S. Payne (Merion Station, Pa.) and Christoph T. Ellebrecht (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention includes compositions comprising a chimeric antigen receptor (CAR) specific for an GD T Cell receptor (anti-GD TCR CAR), vectors comprising the same, compositions comprising anti-GD TCR CAR vectors packaged in viral particles, and recombinant T cells or other effector cells comprising the anti-GD TCR CAR of...