US Patent Issued to The Trustees of the University of Pennsylvania on Feb. 18 for "Use of gene editing to generate universal TCR re-directed t cells for adoptive immunotherapy" (New Jersey, Pennsylvania Inventors)

ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,227,555, issued on Feb. 18, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Use of gene editing to generate universal TCR re-directed t cells for adoptive immunotherapy" was invented by Yangbing Zhao (Lumberton, N.J.), Xiaojun Liu (Wallingford, Pa.) and Wei Pan (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention includes compositions and methods for a modified immune cell or precursor cell thereof comprising an inducible expression system. Also provided are gene edited modified immune cells suitable for T cell therapy. Methods of treatment using modified immune cells of the present invention...