ALEXANDRIA, Va., Feb. 12 -- United States Patent no. 12,221,615, issued on Feb. 11, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).
"GLP-1 and use thereof in compositions for treating metabolic diseases" was invented by Christian Hinderer (Philadelphia), James M. Wilson (Philadelphia) and Matthew Wilson (Philadelphia).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for treating type II diabetes in a subject. A viral vector is provided which includes a nucleic acid molecule comprising a sequence encoding a propeptide and the active portion of GLP-1, wherein, when expressed, the N-terminal amino acid of GLP-1 immediately follows the C-terminal amino acid of...