US Patent Issued to The Trustees of the University of Pennsylvania on Dec. 2 for "'Smart' hydrogel for the radiosensitization and sustained delivery of therapeutics triggered by irradiation" (Pennsylvania, New York Inventors)

ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,401, issued on Dec. 2, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"'Smart' hydrogel for the radiosensitization and sustained delivery of therapeutics triggered by irradiation" was invented by Mathilde Bouche (Philadelphia), David Cormode (Philadelphia), Saad Sheikh (Pittsford, N.Y.) and Jay Dorsey (Media, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a hydrogel for comprising a biodegradable polyphosphazene polymer, a radiation-sensitive diselenide cross-linker; and one or more payloads releasably loaded within the hydrogel. The present invention further provides methods for radi...