ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,458,604, issued on Nov. 4, was assigned to The Trustees of the University of Pennsylvania (Philadelphia) and George Mason Research Foundation Inc. (Fairfax, Va.).

"Methods of lipid nanoparticle manufacture and compositions derived therefrom" was invented by Michael Daro Buschmann (Fairfax, Va.), Mikell Paige (Fairfax, Va.), Suman Alishetty (Fairfax, Va.), Manuel Carrasco (Fairfax, Va.), Mohamad Gabriel Alameh (Fairfax, Va.) and Drew Weissman (Fairfax, Va.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods of increasing the potency of nucleic acid loaded lipid nanoparticles (naLNPs) through certain novel and surprisingly superior ...