US Patent Issued to THE TRUSTEES OF INDIANA UNIVERSITY on Sept. 9 for "Repurposing FDA-approved drugs as a novel cancer therapeutic avenue through inhibition of PRMT5" (Indiana, Connecticut Inventors)

ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,409,173, issued on Sept. 9, was assigned to THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Ind.).

"Repurposing FDA-approved drugs as a novel cancer therapeutic avenue through inhibition of PRMT5" was invented by Tao Lu (Carmel, Ind.), Matthew Martin (Indianapolis) and Lakshmi Milind Prabhu (Ridgefield, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods of inhibiting a protein arginine methyltransferase by contacting the methyltransferase with a compound selected from the group consisting of cloperastine hydrochloride, candesartan cilexetil, or analog of such compounds, and combinations thereof. One embodiment of the pre...