US Patent Issued to THE TRUSTEES OF DARTMOUTH COLLEGE on July 1 for "Chimeric antigen receptors for treatment of neurodegenerative diseases and disorders" (New Hampshire Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,662, issued on July 1, was assigned to THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, N.H.).

"Chimeric antigen receptors for treatment of neurodegenerative diseases and disorders" was invented by Charles Sentman (Grantham, N.H.), David Graber (Hanover, N.H.) and W. James Cook (Hanover, N.H.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure generally relates to novel chimeric antigen receptors ("CARs"), modified regulatory T cells ("Tregs") expressing such CARs and/or Tregs which are engineered to express neurodegenerative disease modifying molecules, e.g., which express molecules which prevent oxidative/inflammatory activity, or whic...