ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,384,827, issued on Aug. 12, was assigned to THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, N.H.).
"Chimeric NK receptor and methods for treating cancer" was invented by Tong Zhang (Beijing) and Charles L. Sentman (West Lebanon, N.H.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to chimeric immune receptor molecules for reducing or eliminating tumors. The chimeric receptors are composed a C-type lectin-like natural killer cell receptor, or a protein associated therewith, fused to an immune signaling receptor containing an immunoreceptor tyrosine-based activation motif. Methods for using the chimeric receptors are further provi...