US Patent Issued to The Trustees of Columbia University in the City of New York on Sept. 23 for "Gene therapy for diseases caused by unbalanced nucleotide pools including mitochondrial DNA depletion syndromes" (American, Spanish Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,419,970, issued on Sept. 23, was assigned to The Trustees of Columbia University in the City of New York (New York).

"Gene therapy for diseases caused by unbalanced nucleotide pools including mitochondrial DNA depletion syndromes" was invented by Michio Hirano (New York), Hasan O. Akman (Haworth, N.J.) and Carlos Lopez-Gomez (Fuengirola, Spain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates generally to a method of treatment for a human genetic disease, such as diseases characterized by unbalanced nucleotide pools, e.g., mitochondrial DNA depletion syndromes, and more specifically, thymidine kinase 2 (TK2) deficiency, using gene th...