ALEXANDRIA, Va., June 9 -- United States Patent no. 12,285,464, issued on April 29, was assigned to The Trustees of Columbia University in the City of New York (New York) and The Brigham and Women's Hospital Inc. (Boston).
"Therapeutic targets involved in the progression of nonalcoholic steatohepatitis (NASH)" was invented by Ira Tabas (New City, N.Y.), Xiaobo Wang (Fort Lee, N.J.), Omid Farokhzad (Waban, Mass.) and Xiaoding Xu (Malden, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to methods and compositions for specifically modulating the Hippo pathway transcription factor TAZ (WWTR1), as a therapeutic target for inhibiting or preventing liver conditions including the p...