ALEXANDRIA, Va., July 9 -- United States Patent no. 12,350,297, issued on July 8, was assigned to THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York) and NATIONAL INSTITUTES OF HEALTH (NIH) U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS) (Bethesda, Md.).

"Programmable bacteria for the treatment of cancer" was invented by Tal Danino (New York), Nicholas Arpaia (New York), Sreyan Chowdhury (New York) and Candice Gurbatri (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are programmable bacteria for tumor-targeted immunotherapeutic delivery. In certain embodiments, the programmable bacteria comprise at least one synchronized lysis circuit contained in a single operon w...