US Patent Issued to THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY on Dec. 16 for "Inhibitor of EIF2Alpha dephosphorylation" (Canadian Inventors)

ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,358, issued on Dec. 16, was assigned to THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (Montreal, Canada).

"Inhibitor of EIF2Alpha dephosphorylation" was invented by Jean-Philip Lumb (Montreal, Canada) and Colin Crist (Montreal, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to a compound of formula (I)where R1 is as defined herein. The compound of formula I is an inhibitor of the dephosphorylation of phosphorylated elF2Alpha. The phosphorylation of elF2Alpha affects the quiescence and self renewal properties of stem cells such as muscle stem cells. The compound of formula (I) can thus b...