ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,527,840, issued on Jan. 20, was assigned to THE ROCKEFELLER UNIVERSITY (New York).
"Methods of treating fulminant viral hepatitis with an IL-18 antagonist in a patient with an IL-18BP variant" was invented by Jean-Laurent Casanova (NY, N.Y.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to mutations and alterations in the inflammatory pathway, including IL-18BP and IL-10RB mutations, that are associated with the development of fulminant viral hepatitis following viral infection, such as following hepatitis virus infection. The invention relates to methods for treating or ameliorating viral hepatitis comprising administering IL-18BP...