US Patent Issued to The Research Foundation for The State University of New York on June 17 for "Genome edited cancer cell vaccines" (New York Inventors)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,320, issued on June 17, was assigned to The Research Foundation for The State University of New York (Binghamton, N.Y.).

"Genome edited cancer cell vaccines" was invented by Kaiming Ye (Vestal, N.Y.), Sha Jin (Vestal, N.Y.) and Subhadra Jayaraman Rukmini (Binghamton, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A cancer vaccine technology is provided which knocks out expression of cell surface immune checkpoint proteins, to facilitate their processing by immune cells, and optionally by knocking-in the expression of cytokines to boost immune response. Non-replicating tumor cells lacking cell surface CD47 are highly effective immunizing agents ...