US Patent Issued to The Research Foundation for The State University of New York on July 29 for "5-halouracil-modified micrornas and their use in the treatment of cancer" (New York Inventors)

ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,693, issued on July 29, was assigned to The Research Foundation for The State University of New York (Albany, N.Y.).

"5-halouracil-modified micrornas and their use in the treatment of cancer" was invented by Jingfang Ju (East Setauket, N.Y.) and Andrew Fesler (Sound Beach, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides nucleic acid compositions that incorporate one or more halouracil molecules. More specifically, the present disclosure reveals that the replacement of uracil nucleotides within a microRNA nucleotide sequence with a 5-halouracil increases the ability of the micro-RNA to inhibit cancer progression an...