US Patent Issued to THE REGENTS OF THE UNIVERSITY OF MICHIGAN on Sept. 30 for "Chimeric antigen receptors targeting abnormal glycobiology" (Maryland, Michigan Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,463, issued on Sept. 30, was assigned to THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Mich.).

"Chimeric antigen receptors targeting abnormal glycobiology" was invented by Challice L. Bonifant (Towson, Md.), Alnawaz Rehemtulla (Plymouth, Mich.) and David M. Markovitz (Ann Arbor, Mich.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides a chimeric antigen receptor (CAR) polypeptide having an antigen binding domain comprising an extracellular lectin which specifically binds to glycoproteins expressed on the surface of target cells. Also provided herein are engineered lymphocytes expressing the CAR polypeptide, a nucleic aci...