US Patent Issued to The Regents of the University of California on Nov. 4 for "Tough tissue sealants and the use thereof" (Pennsylvania, California Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,458,728, issued on Nov. 4, was assigned to The Regents of the University of California (Oakland, Calif.).

"Tough tissue sealants and the use thereof" was invented by Amir Sheikhi (State College, Pa.), Maryam Tavafoghi (Los Angeles) and Alireza Khademhosseini (Los Angeles).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides injectable, tough hydrogels that can be crosslinked in situ on demand using minimally-invasive methods, such as visible light exposure is an unmet medical challenge. Among the emerging biopolymers for tissue sealing, gelatin methacryloyl (GelMA), a naturally-derived biopolymer obtained from denatured collagen, has secu...