US Patent Issued to The Regents of the University of California on Nov. 25 for "Chimeric antigen receptors and related methods and compositions for the treatment of cancer" (California Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,479,923, issued on Nov. 25, was assigned to The Regents of the University of California (Oakland, Calif.).

"Chimeric antigen receptors and related methods and compositions for the treatment of cancer" was invented by Yvonne Yu-Hsuan Chen (Los Angeles), Ximin Chen (Los Angeles) and Laurence Chen (Walnut, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to novel scFv molecules that are useful for incorporation into novel chimeric antigen receptors with enhance anti-tumor activity. Further aspects relate to a polypeptide comprising a CAR comprising, in order from amino proximal to carboxy proximal end, a scFv, a transm...