ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,965, issued on Nov. 25, was assigned to The Regents of the University of California (Oakland, Calif.).

"Cavity acoustic transducer (CAT) for shear-induced cell transfection" was invented by Abraham P. Lee (Irvine, Calif.), Mohammad Aghaamoo (Irvine, Calif.), Xuan Li (Irvine, Calif.), Neha Garg (Irvine, Calif.) and Yu-Hsi Chen (Irvine, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention features the use of cavity acoustic transducers (CATs) to apply mechanical stimuli on cells. CATs utilize the generated acoustic microstreaming vortices to trap cells and apply tunable shear on them. The present invention may use such a portabl...