US Patent Issued to The Regents of the University of California on May 27 for "Compositions and methods of treating ocular diseases" (California Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,310,997, issued on May 27, was assigned to The Regents of the University of California (Oakland, Calif.).

"Compositions and methods of treating ocular diseases" was invented by David V. Schaffer (Danville, Calif.), Leah C. Byrne (San Francisco), Timothy P. Day (Berkeley, Calif.) and John G. Flannery (Berkeley, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides recombinant adeno-associated virus (AAV) virions with altered capsid protein, where the recombinant AAV (rAAV) virions exhibit greater ability to cross barriers between intravitreal fluid and retinal cells, and thus greater infectivity of a retinal cell compared ...