US Patent Issued to The Regents of the University of California on May 27 for "Biomarker for thoracic aortic aneurysm" (California Inventor)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,313,635, issued on May 27, was assigned to The Regents of the University of California (Oakland, Calif.).

"Biomarker for thoracic aortic aneurysm" was invented by Hua Cai (Los Angeles).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for detecting thoracic aortic aneurysm (TAA) or predisposition to TAA in a subject comprises measuring the amount of tetrahydrobiopterin (H4B) present in the test sample; and comparing a measured amount of HUB to a standard amount of H4B. A decreased amount of H4B present in the test sample compared to the standard is indicative of TAA or predisposition to TAA. The method can further comprise identifying a candidate f...