ALEXANDRIA, Va., June 19 -- United States Patent no. 12,329,931, issued on June 17, was assigned to The Regents of the University of California (Oakland, Calif.).

"System and method for closed-loop patient-adaptive hemodynamic management" was invented by Joseph B. Rinehart (Newport Beach, Calif.) and Maxime Cannesson (Irvine, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A system and method for patient-adaptive hemodynamic management is described. One embodiment includes a system for hemodynamic management including transfusion, volume resuscitation with intravenous fluids, and medications, utilizing monitored hemodynamic parameters including the described dynamic predictors of fluid responsiveness, ...