ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,286, issued on June 17, was assigned to The Regents of the University of California.
"Methods of adding polymers to ribonucleic acids" was invented by Manuel Ares Jr. (Santa Cruz, Calif.), Logan Mulroney (Santa Cruz, Calif.), Jenny Vo (Santa Cruz, Calif.) and Mark Akeson (Santa Cruz, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are methods of adding a polymer of non-canonical nucleotides to the 3' end of a ribonucleic acid (RNA). In certain embodiments, the methods comprise combining an RNA, a polynucleotide-3' nucleotidyl transferase, and non-canonical nucleotides, in a reaction mixture under conditions in which the polynucleotide...