US Patent Issued to The Regents of the University of California on June 10 for "Macropinocytosing human anti-CD46 antibodies and targeted cancer therapeutics" (California Inventors)

ALEXANDRIA, Va., June 18 -- United States Patent no. 12,325,755, issued on June 10, was assigned to The Regents of the University of California (Oakland, Calif.).

"Macropinocytosing human anti-CD46 antibodies and targeted cancer therapeutics" was invented by Bin Liu (San Francisco), Yang Su (South San Francisco, Calif.), Scott Bidlingmaier (San Francisco), Christopher R. Behrens (San Francisco) and Namkyung Lee (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "In various embodiments human anti-CD46 antibodies that are internalizing and enter tumor cells via the macropinocytosis pathway are provided, as well as antibody-drug conjugates (ADCs) developed from these antibodies for diagnostic and/or t...