US Patent Issued to The Regents of the University of California on July 29 for "Chimeric antigen receptor and methods of use thereof" (California Inventors)

ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,466, issued on July 29, was assigned to The Regents of the University of California (Oakland, Calif.).

"Chimeric antigen receptor and methods of use thereof" was invented by Chia-Yung Wu (San Francisco), James Onuffer (Alameda, Calif.) and Wendell A. Lim (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence encoding the CAR. The present disclosure provides cells genetically modified to produce the CAR. A CAR of the present disclosure can be used in various methods, which are also provided....