US Patent Issued to The Regents of the University of California on July 1 for "CLAUDIN18 antibodies and methods of treating cancer" (California Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,345,709, issued on July 1, was assigned to The Regents of the University of California (Oakland, Calif.).

"CLAUDIN18 antibodies and methods of treating cancer" was invented by Dylan Conklin (Los Angeles), Martina S. McDermott (Los Angeles), Neil A. O'Brien (Los Angeles), Michael J. Palazzolo (Los Angeles) and Dennis Slamon (Los Angeles).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides antigen-binding proteins which bind to Claudin-18.2 (CLDN18.2); bispecific antigen-binding proteins which bind to CLDN18.2 and a second antigen; and conjugates thereof. In various aspects, the antigen-binding proteins bind to Extracellular Loop ...