US Patent Issued to The Regents of the University of California on Feb. 18 for "Modulators of CAS9 polypeptides and methods of use thereof" (California Inventors)

ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,227,547, issued on Feb. 18, was assigned to The Regents of the University of California (Oakland, Calif.).

"Modulators of CAS9 polypeptides and methods of use thereof" was invented by Jennifer A. Doudna (Berkeley, Calif.), Kyle E. Watters (Moraga, Calif.), Haridha Shivram (Berkeley, Calif.) and Christof Fellmann (Berkeley, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides AcrIIA7 polypeptides, nucleic acids encoding the AcrIIA7 polypeptides, and kits comprising the AcrIIA7 polypeptides and/or nucleic acids encoding the ACRIIA7 polypeptides. The present disclosure provides methods of inhibiting an activity of a Cas9 po...