US Patent Issued to The Regents of the University of California on Aug. 26 for "Technology for improving properties of lipid nanoparticles using lipids in which cis-unsaturated bonds are substituted with a silicon atom" (California Inventors)

ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,396,949, issued on Aug. 26, was assigned to The Regents of the University of California (Oakland, Calif.).

"Technology for improving properties of lipid nanoparticles using lipids in which cis-unsaturated bonds are substituted with a silicon atom" was invented by Annaliese Franz (Davis, Calif.), Angel Cobo (Davis, Calif.), Leah Thompson (Davis, Calif.) and David Coppage (Davis, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides silyl lipid molecules in which one or more carbon-to-carbon double bonds in the lipophilic portion is substituted with a silicon atom. Guidance is provided by which the reader may make silyl lipid mole...