US Patent Issued to The Regents of the University of California on April 8 for "Compounds and methods for synergistic activation of M channels" (California Inventors)

ALEXANDRIA, Va., April 9 -- United States Patent no. 12,268,683, issued on April 8, was assigned to The Regents of the University of California (Oakland, Calif.).

"Compounds and methods for synergistic activation of M channels" was invented by Geoffrey W. Abbott (Irvine, Calif.) and Rian W. Manville (Irvine, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of activating heteromeric KCNQ2/3, KCNQ3/5, or KCNQ4/5 voltage-gated potassium channels in a cell membrane is described, as are compositions for use with same, as well as methods of reducing neuronal excitability and of ameliorating symptoms of epilepsy, anxiety, neuropathic pain, hypertension, cardiovascular disease, a neurodegenerative diso...