US Patent Issued to The Regents of the University of California, University of Vienna on Feb. 4 for "Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription" (Austrian, American, German Inventors)

ALEXANDRIA, Va., Feb. 5 -- United States Patent no. 12,215,343, issued on Feb. 4, was assigned to The Regents of the University of California (Oakland, Calif.) and University of Vienna (Vienna).

"Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription" was invented by Jennifer A. Doudna (Berkeley, Calif.), Martin Jinek (Berkeley, Calif.), Krzysztof Chylinski (Vienna) and Emmanuelle Charpentier (Berlin).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypepti...