ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,725, issued on Oct. 28, was assigned to The Johns Hopkins University (Baltimore).
"Method of detecting cancer through generalized loss of stability of epigenetic domains and compositions thereof" was invented by Andrew P. Feinberg (Lutherville, Md.) and Rafael I. Irizarry (Brookline, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein is a method of detecting cancer through generalized loss of stability of epigenetic domains as well as compositions useful therein. The present invention is based on the discovery that generalized loss of stability of epigenetic domains was determined to be a characteristic across various cancer types....