US Patent Issued to The Johns Hopkins University on May 27 for "Compositions and methods for targeting activin signaling to treat cancer" (Maryland, New York, Texas Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,398, issued on May 27, was assigned to The Johns Hopkins University (Baltimore).

"Compositions and methods for targeting activin signaling to treat cancer" was invented by Fan Pan (Baltimore), Duojia Pan (Dallas), Drew M. Pardoll (Brookeville, Md.), Joseph Barbi (East Amherst, N.Y.), Juan Fu (Lutherville, Md.), Ying Zheng (Baltimore) and Andriana Lebid (Baltimore).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compositions and methods for treating cancer by targeting the Activin signaling pathway. In certain embodiments, combining Activin blockade with immunomodulation alters regulatory T (Treg) cell-mediated immune r...