US Patent Issued to The Johns Hopkins University on May 20 for "Combinatory treatment strategies of cancer based on RNA polymerase I inhibition" (Maryland Inventors)

ALEXANDRIA, Va., June 16 -- United States Patent no. 12,303,508, issued on May 20, was assigned to The Johns Hopkins University (Baltimore).

"Combinatory treatment strategies of cancer based on RNA polymerase I inhibition" was invented by Marikki K. Laiho (Baltimore), Hester Hui Liu (Cockeysville, Md.), Paul Sirajuddin (Baltimore) and Elina Ikonen (Baltimore).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are compositions comprising a combination of at least one Pol I inhibitor, and at least one autophagy inhibiting compound, and/or at least one ACAT1 inhibiting compound, and/or at least one PARP inhibiting compound and their use in treating cancers and other related neoplastic diseases and w...