US Patent Issued to The Johns Hopkins University on July 22 for "Combined MAPK and NAMPT inhibition for treatment of neuron degeneration" (Maryland Inventors)

ALEXANDRIA, Va., July 23 -- United States Patent no. 12,364,681, issued on July 22, was assigned to The Johns Hopkins University (Baltimore).

"Combined MAPK and NAMPT inhibition for treatment of neuron degeneration" was invented by Vassilis E. Koliatsos (Baltimore), Athanasios Alexandris (Baltimore) and Jiwon Ryu (Baltimore).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods for inhibiting or preventing neuron injury or death. The methods comprise contacting one or more neurons with small molecule modulators of one or more mitogen-activated kinase kinase kinases (MAP3Ks), a nicotinamide phosphoribosyltransferase (NAMPT), or a combination thereof."

The patent was filed on Jan. 7, 2022,...