US Patent Issued to The Johns Hopkins University on July 15 for "Methods and compositions for infusion of transiently engrafting, selected populations of allogeneic lymphocytes to treat cancer" (Maryland Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,359,167, issued on July 15, was assigned to The Johns Hopkins University (Baltimore).

"Methods and compositions for infusion of transiently engrafting, selected populations of allogeneic lymphocytes to treat cancer" was invented by Ephraim Joseph Fuchs (Owings Mills, Md.), Heather Jill Symons (Annapolis, Md.) and Lode Swinnen (Lutherville, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides methods and compositions for administration of allogeneic lymphocytes as an exogenous source of CD4+ T cell help for endogenous, tumor-reactive CD8+ T cells. Depletion of CD8+ T cells from the donor lymphocyte infusion reduces the risk of sustai...