US Patent Issued to The Johns Hopkins University on Feb. 17 for "Generation and cryopreservation of pluripotent stem cell-derived clinical grade corneal endothelial cells" (Maryland Inventors)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,553,027, issued on Feb. 17, was assigned to The Johns Hopkins University (Baltimore).

"Generation and cryopreservation of pluripotent stem cell-derived clinical grade corneal endothelial cells" was invented by S. Amer Riazuddin (Baltimore), John Gottsch (Baltimore), Shahid Khan (Baltimore) and Muhammad Ali (Baltimore).

According to the abstract* released by the U.S. Patent & Trademark Office: "Human embryonic stem cell (hESC)- and induced pluripotent stem cell (iPSC)-derived clinical-grade corneal endothelial cells (CECs) generation and cryopreservation through the neural crest cell (NCC) lineage using peripheral blood as a donor source and hESCs maximizes the availability of these v...