ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,409,237, issued on Sept. 9, was assigned to The Jackson Laboratory (Bar Harbor, Maine) and University of Massachusetts (Westborough, Mass.).
"Methods and models for assessing efficacy of immunotherapies" was invented by Leonard D. Shultz (Bar Harbor, Maine), James Keck (Bar Harbor, Maine), Dale L. Greiner (Westborough, Mass.) and Michael A. Brehm (Westborough, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method of identifying anti-tumor activity of a test substance is provided along with a genetically-modified, immunodeficient mouse and methods of use, wherein the genetically-modified, immunodeficient mouse enables in vivo investigation of th...