US Patent Issued to The Heart Research Institute on Aug. 12 for "Detection of high-risk unstable atherosclerotic plaque" (Australian Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,383,158, issued on Aug. 12, was assigned to The Heart Research Institute Ltd (Newtown, Australia).

"Detection of high-risk unstable atherosclerotic plaque" was invented by Roland Stocker (Sydney) and Imran Rashid (Sydney).

According to the abstract* released by the U.S. Patent & Trademark Office: "The technology relates to a method for detecting high-risk unstable atherosclerotic plaque in a subject, the method comprising: a) administering to the subject a magnetic resonance imaging (MRI) contrast agent capable of being activated by myeloperoxidase (MPO) in atherosclerotic plaque; b) allowing the contrast agent to be activated by myeloperoxidase in atherosclerotic plaque; c) obtainin...