US Patent Issued to The General Hospital, President and Fellows of Harvard College on June 3 for "Enhanced virus-like particles and methods of use thereof for delivery to cells" (Massachusetts Inventors)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,319,938, issued on June 3, was assigned to The General Hospital Corp. (Boston) and President and Fellows of Harvard College (Cambridge, Mass.).

"Enhanced virus-like particles and methods of use thereof for delivery to cells" was invented by J. Keith Joung (Winchester, Mass.) and Peter Cabeceiras (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Enhanced virus-like particles (eVLPs), comprising a membrane comprising a phospholipid bilayer with one or more virally-derived glycoproteins on the external side; and a cargo disposed in the core of the eVLP on the inside of the membrane, wherein the eVLP does not comprise an exogenous gag/pol protein, and m...