ALEXANDRIA, Va., July 9 -- United States Patent no. 12,350,290, issued on July 8, was assigned to The General Hospital Corp. (Boston) and Massachusetts Institute Of Technology (Cambridge, Mass.).

"Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders" was invented by Vamsi K. Mootha (Boston), Isha Jain (Cambridge, Mass.), Warren M. Zapol (Cambridge, Mass.) and Luca Zazzeron (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "A system includes an enclosed tent or chamber or a breathing apparatus, a hypoxia induction system and a device for measuring arterial oxygen saturation in a subject breathing air ...