ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,298, issued on Dec. 2, was assigned to THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami) and UNIVERSITY OF FLORENCE (Florence, Italy).
"Fucosyltransferase specific inhibition using fucose mimetics" was invented by Robert Sackstein (Miami), Barbara Richichi (Florence, Italy) and Kyle Martin (Miami).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are compositions and methods for specific fucosyltransferase inhibition for treatment of a variety of diseases. The compositions of the invention comprise a glycomimetic of L-Fucose that selectively inhibits the generation of sialyl Lewis X by FTVI and FTVII but has no effect on the generat...