ALEXANDRIA, Va., June 25 -- United States Patent no. 12,337,040, issued on June 24, was assigned to THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Mo.).
"Dystrophin R16/R17 syntrophin PDZ fusion proteins" was invented by Dongsheng Duan (Columbia, Mo.), Yi Lai (Columbia, Mo.), Junling Zhao (Columbia, Mo.) and Yongping Yue (Columbia, Mo.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Synthetic nucleic acids encoding mini and microdystrophin genes comprising the membrane binding motifs or domains of the R10-R11-R12 region are provided. Also provided are vectors, host cells, and related methods of using the same to treat a subject suffering from Duchenne muscular dystrophy (DMD), Becker muscular dystrophy...