US Patent Issued to The Cleveland Clinic Foundation on Aug. 12 for "Allosteric activators of the ALPHA 1A -adrenergic receptor" (Ohio Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,384,751, issued on Aug. 12, was assigned to The Cleveland Clinic Foundation (Cleveland).

"Allosteric activators of the ALPHA 1A -adrenergic receptor" was invented by Dianne M. Perez (Cleveland), Shaun R. Stauffer (Cleveland) and Jonathan Macdonald (Cleveland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds that are activators of the Alpha1A-Adrenergic Receptor (Alpha1A-AR) and methods of using such compounds: for treating neurological conditions, for cardio-protection, and for treating other conditions. In certain embodiments, the Alpha1A-AR activator compound is a compound of Formula I. In certain embodiments, t...