US Patent Issued to The Children's Mercy Hospital, The University of Kansas on July 22 for "Engineered regulatory T cells" (Kansas, Missouri Inventors)

ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,918, issued on July 22, was assigned to The Children's Mercy Hospital (Kansas City, Mo.) and The University of Kansas (Lawrence, Kan.).

"Engineered regulatory T cells" was invented by Amara Seng (Kansas City, Kan.), Ryan Fischer (Shawnee, Kan.), Thomas Yankee (Overland Park, Kan.), Mary Markiewicz (Leawood, Kan.) and John Szarejko (Liberty, Mo.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Cell therapy compositions comprising engineered human regulatory T cells (eTregs) characterized by ectopic overexpression of FOXP3 and Helios protein, produced via introduction of separate nucleic acid constructs respectively encoding FOXP3 and Helios (FOXP3+Heli...