US Patent Issued to THE CHILDREN'S MEDICAL CENTER on July 8 for "BCL11A microRNAs for treating hemoglobinopathies" (Massachusetts Inventors)

ALEXANDRIA, Va., July 9 -- United States Patent no. 12,350,284, issued on July 8, was assigned to THE CHILDREN'S MEDICAL CENTER Corp..

"BCL11A microRNAs for treating hemoglobinopathies" was invented by David A. Williams (Dover, Mass.) and Swaroopa Guda (Canton, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Embodiments herein provide specially designed synthetic BCL11A-targeting microRNAs for RNA polymerase II expression, and methods of use to treat hemoglobinopathies, such as sickle cell disease or thalassemia, by increasing the expression levels of fetal hemoglobin levels."

The patent was filed on April 30, 2019, under Application No. 17/051,578.

*For further information, including images, charts a...