ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,346, issued on June 17, was assigned to The Children's Medical Center Corp. and The United States of America As Reprsented by the Secretary Department of Health & Human Services.
"Selective oxidation of 5-methylcytosine by TET-family proteins" was invented by Anjana Rao (La Jolla, Calif.), Mamta Tahiliani (New York), Kian Peng Koh (Jamaica Plain, Mass.), Suneet Agarwal (Belmont, Mass.) and Aravind Iyer (Bethesda, Md.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising ca...