ALEXANDRIA, Va., July 16 -- United States Patent no. 12,357,694, issued on July 15, was assigned to The Children's Hospital of Philadelphia (Philadelphia).
"Methods and compositions for use of tumor self-antigens in adoptive immunotherapy" was invented by John M Maris (Philadelphia) and Mark Yarmarkovich (Philadelphia).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods and compositions for immunotherapy employing a modified T cell or NK cell comprising a receptor that binds to newly identified tumor antigens that can be administered to patients for disease (e.g., cancer) treatment. Also described are polynucleotides and vectors encoding the same."
The patent was filed on M...